Friday, April 8, 2016

We are rolling again on Sunday, May 22nd to support The NU/UC Tolerance Initiative

Dr. Stephen D. Miller from Northwestern and Dr. Brian Popko from the University of Chicago are using nanotechnology to induce immune system tolerance, thereby preventing “friendly fire” on healthy cells in the body of a patient with MS.

In this work, biodegradable nanoparticles—composed of the same biopolymer used to make resorbable sutures—are coated with myelin proteins. Once these clusters are infused into the body, the immune system is re-taught that healthy myelin is not an invading outside threat and should be left alone. The Miller and Popko laboratories are combining this tolerance protocol with drugs that stimulate myelin repair and have found that combined treatment with both strategies leads to a remarkable ability to reverse paralytic symptoms in animal models of MS. 

Through the Tolerance Initiative, the immune system environment is effectively enhanced, allowing for re-myelination to occur naturally or with the intervention of myelin repair agents, many of which are currently entering into human clinical trials.

This research is a game changer. Not only does it have the potential to revolutionize the management of MS, but also myriad other diseases. Since the myelin proteins used in the Tolerance Initiative can be exchanged with other proteins, scientists could potentially “tolerize” in response to many types of autoimmune diseases, including type 1 diabetes, rheumatoid arthritis, and lupus. It could also lead to breakthroughs in controlling severe allergies like peanut and cat dander, or even eliminating organ transplant rejections.

Join us and be part of our team; walk and donate on Sunday, May 22nd, 2016  in Lincolnshire.  At 10:00 am we will start a 4 mile neighborhood walk, starting and finishing at our house. Then spend the afternoon of camaraderie and a backyard picnic with us. Bring your friends.

If you can’t make the trip join our group by donating online through Northwestern Univ.

or by writing a check:
Northwestern Univ.
CATalyzer project, FAKGA
c/o Bob Gregory
10 Londonderry Lane
Lincolnshire, IL 60069
It’s tax deductible!

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